Born in Wu commandery, she lost her parents at a young age so lived with her younger brother Wu Jing. When Sun Jian sought to marry her, her relatives disaproved of him and where going to refuse Sun Jian but Lady Wu persuaded them to let her marry him to avoid risk to the family. She would bear Sun Jian four boys, including Sun Ce and Sun Quan, and one daughter, Sun Shangxiang. Lady Wu showed a willingness to appeal on behalf of others to Sun Ce, two of her success being for Wang Sheng and Wei Ting. Lady Wu assisted a young Sun Quan in civil and military matters and was described as helpful. In the 7th year of Jian’an, she held audience on her deathbed with Zhang Zhao and his cohorts, giving him her last will.
- Wu Jing - brother